Description
SS-31 (Elamipretide) is a synthetic, mitochondria-targeted tetrapeptide developed for advanced research into mitochondrial bioenergetics, oxidative stress, and cellular resilience. Unlike conventional antioxidants that act diffusely within the cytosol, SS-31 is uniquely designed to selectively localize to the inner mitochondrial membrane, where it interacts directly with cardiolipin, a phospholipid essential for electron transport chain integrity and ATP production.
This targeted mechanism allows SS-31 to modulate mitochondrial function at its point of greatest vulnerability, making it a powerful research tool for studying mitochondrial dysfunction across cardiovascular, metabolic, neurodegenerative, and age-related models.


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