KPV 10mg

Description

KPV (Lysine–Proline–Valine) is a naturally occurring tripeptide fragment derived from the C-terminal sequence of alpha-melanocyte-stimulating hormone (α-MSH), a peptide within the proopiomelanocortin (POMC) family. KPV retains α-MSH’s potent anti-inflammatory and immunomodulatory actions while being non-pigmentary and exhibiting exceptional biostability and tissue permeability.

KPV functions as a selective melanocortin-1 receptor (MC1R) agonist and an NF-κB pathway inhibitor, positioning it as a key modulator in the body’s innate anti-inflammatory and repair systems. It helps restore epithelial barrier function, downregulate pro-inflammatory cytokines, and support gut and skin homeostasis, making it an important peptide in protocols targeting autoimmunity, inflammatory bowel conditions, and post-injury recovery.